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KMID : 0358320140550030182
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Korean Journal of Urology
2014 Volume.55 No. 3 p.182 ~ p.189
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Treatment Outcomes of Transurethral Macroplastique Injection for Postprostatectomy Incontinence
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Lee Sin-Woo
Kang Jung-Hun
Sung Hyun-Hwan
Jeong U-Seok
Lee Young-Suk
Baek Min-Ki
Lee Kyu-Sung
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Abstract
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Purpose: We investigated the efficacy of transurethral injection of Macroplastique bulking agent (Uroplasty) for male stress urinary incontinence (SUI) after prostate surgery.
Materials and Methods: This retrospective review included men with SUI treated by transurethral injection for symptoms resulting from prostate surgery. Patients were evaluated at 1 month and 6 months after injection by determining the number of pads used per day and changes in incontinence symptoms. Treatment success was defined as use of 1 pad or fewer per day combined with subjective symptom improvement.
Results: The study population comprised 30 men with a mean age of 66.1±5.3 years. Of the 30 patients, 24 (80.0%) underwent prostate cancer surgery and the remaining 6 (20.0%) underwent surgery for benign prostatic hyperplasia. The preinjection pad number was 2.9±1.9 pads per day. After injection treatment, the mean follow-up period was 9.3±12.7 months and the success rate was 43% (13/30) at 1 month and 32% (6/19) at 6 months. Injection was more likely to result in a successful outcome in patients with no preinjection radiation treatment history and higher abdominal leak point pressure (ALPP) than in those with a previous history of radiation treatment and lower ALPP, although this result was not statistically significant. Acute urinary retention occurred in 5 patients (17%).
Conclusions: Transurethral Macroplastique injection treatment is a relatively non-invasive treatment method for male SUI with a success rate of 43% at 1 month and 32% at 6 months. Patients with a higher ALPP and no previous history of radiation therapy may experience better treatment outcomes.
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KEYWORD
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Dimethylpolysiloxanes, Male, Prostate, Urethra, Urinary incontinence
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